Biocompatibility of Coronary Stents

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Biocompatibility of Coronary Stents

Cardiovascular disease is the dominant cause of mortality in developed countries, with coronary artery disease (CAD) a predominant contributor. The development of stents to treat CAD was a significant innovation, facilitating effective percutaneous coronary revascularization. Coronary stents have evolved from bare metal compositions, to incorporate advances in pharmacological therapy in what ar...

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Biocompatibility of phosphorylcholine coated stents in normal porcine coronary arteries.

OBJECTIVE To improve the biocompatibility of stents using a phosphorylcholine coated stent as a form of biomimicry. INTERVENTIONS Implantation of phosphorylcholine coated (n = 20) and non-coated (n = 21) stents was performed in the coronary arteries of 25 pigs. The animals were killed after five days (n = 6), four weeks (n = 7), and 12 weeks (n = 8), and the vessels harvested for histology, s...

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Biocompatibility of phosphorylcholine coated stents

Objective—To improve the biocompatibility of stents using a phosphorylcholine coated stent as a form of biomimicry. Interventions—Implantation of phosphorylcholine coated (n = 20) and non-coated (n = 21) stents was performed in the coronary arteries of 25 pigs. The animals were killed after five days (n = 6), four weeks (n = 7), and 12 weeks (n = 8), and the vessels harvested for histology, sca...

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Bioengineering stents with proactive biocompatibility

16008 (2014). 111 Meyers SR, Kenan DJ, Khoo X, Grinstaff MW. A bioactive stent surface coating that promotes endothelialization whilepreventing platelet adhesion. Biomacromolecules 12(3),

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2008: Biocompatibility of Therapeutic Self-Assembled Monolayers for Drug-Eluting Coronary Stents

Gopinath Mani, Bysani Chandrasekar, Dave M. Johnson, Marc Feldman, Devang Patel, and C. Mauli Agrawal. The University of Texas at San Antonio, The University of Texas Health Science Center at San Antonio. Introduction: Commercially available drug-eluting stents (DES) use polymers to coat and release drugs [1]. Evidence suggests that polymer coatings cause adverse reactions to DES [1]. We previo...

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ژورنال

عنوان ژورنال: Materials

سال: 2014

ISSN: 1996-1944

DOI: 10.3390/ma7020769